Case Report
Wallerian Degeneration of the Bilateral Middle Cerebellar Peduncles Secondary to Pontine Infarct
Anusha I1*, Shobana N2, Sacratis M3, Selvakumar CJ4 and Sadeeshkumar V4
1Resident, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
2Professor and HOD, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
3Professor, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
4Assistant Professor, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
2Professor and HOD, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
3Professor, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
4Assistant Professor, Department of Neurology, Coimbatore Medical College, Tamilnadu, India
*Corresponding author:Anusha I, Resident, Department of Neurology, Coimbatore Medical College, Tamilnadu, India. E-mail Id: anushainduri38@gmail.com
Article Information:Submission: 30/09/2024; Accepted: 21/10/2024; Published: 25/10/2024
Copyright: © 2024 Anusha I, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Bilateral middle cerebellar peduncle hyperintensities in MRI can be described in several diseases. Previous studies have indicated that neurodegenerative diseases like OPCA, SDS are most likely to affect bilateral MCP. Recent studies have proven that there are many causes of bilateral MCP involvement of which most common being ACI with arterial occlusion. WD, MSA, NMO, heroin-induced leukoencephalopathy, and PCNSL are other causes. Specific
neuroimaging findings& clinical features help in differentiating such lesions. We present a case of 40year old male presented with recurrent pontine stroke having bilateral middle cerebellar peduncle T2 and FLAIR hyperintensities
in repeat MRI due to Wallerian degeneration secondary to pontine infarction. It is important to know how to differentiate WD from Acute stroke which is highlighted in this study.
Keywords:OPCA: olivopontocerebellar atrophy; SDS: schwamon diamond syndrome; WD: Wallerian degeneration; MCP: middle cerebellar peduncle; ACI: acute cerebral infarction; MSA: multisystem atrophy; NMO: neuromyelitis optica