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Journal of Immunology and Vaccine Technology

Research Article

The Effectiveness of Task-Oriented Functional Electrical Stimulation (FES) in Guillain-Barré Syndrome –A Scoping Review and Case Study

Borah AK1*, Goswami P2 and Saikia H3

1Department of Physiotherpy and Neurological Science, Mahatma Gandhi University, Ri-Bhoi Meghalaya, India,
2Department of Physiotherapy, Mahatma Gandhi University, Ri Bhoi, Meghalaya, India.
3Department of Orthopedics and Rehabilitation, Physiotherapy, Sanjevani Hospital, A T Road, Malegaon, Guwahati, India.
*Corresponding author:Arup Kumar Borah, Department of Physiotherpy and Neurological Science, Mahatma Gandhi University, Ri-Bhoi Meghalaya, India. E-mail Id: barup614@gmail.com
Article Information:Submission: 24/02/2026; Accepted: 12/03/2026; Published: 14/03/2026
Copyright: © 2026 Borah AK, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Guillain-Barré Syndrome is an autoimmune disorder characterized by immune-mediated damage to the peripheral nervous system [Nguyen TP, StatPearls Publishing; 2024 Jan.]. GBS affects sensory, motor and autonomic nerves. There occurs temporary inflammation and demyelination of peripheral nerve myelin sheaths resulting in axonal degeneration. It is the most common cause of rapidly progressive flaccid paralysis. It is believed to be one of a number of related conditions, all sharing a similar underlying autoimmune abnormality, as a group known as anti-GQ1b IgG antibody syndrome. Chronic inflammatory demyelinating (CIDP) is considered the chronic counterpart to Guillain-Barré syndrome [Radiopedia, Guillain-Barré syndrome, available: https://radiopaedia.org/articles/guillain - barre syndrome -2 ].
Keywords:Guillain−Barré Syndrome; Functional electrical stimulation; Neurorehabilitation; Pathogenesis; Acute motor axonal neuropathy