Study background: Malnutrition, particularly micronutrient deficits, is common among cirrhotic patients, necessitating interventions to preserve muscle mass. Late-evening snacks with specific nutritional content are crucial for this population. The pronocte protein powder was developed with nutritional value. Objective: To investigate the glycemic index and glycemic load of pronocte protein powder in healthy human adult participants during fasting conditions. Methods: This was a single-center study, 13 healthy human adult subjects participated, and the data is available for 10 subjects. The study was conducted as per the recommendations of WHO. Results: The peak capillary blood glucose was 108.2±12.9 mg/dL at 45 min in the test group (Pronocte protein powder) and 151.7±23.6 mg/dL at 45 min in the reference group (Glucon-D). The mean blood glucose incremental area under the curve for the test group was 1056.1 mg.min/dL and for the reference group 3932.3 mg.min/dL. Conclusion: The glycemic index of pronocte protein powder was 26.9% which is low as per GI classification. The glycemic load is 2.22 per typical serving of 30gm which is low as per the classification of glycemic load. Pronocte protein powder can serve as a late-night snack. This will prevent the catabolic phase in cirrhosis patients..

Keywords:Malnutrition; Pronocte Protein Powder; Glucon-D; Glycemic Index; Glycemic Load; Cirrhosis