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Indian Journal of Gynecology

Research Article

Comparative Efficacy and Safety of Fosfomycin and Nitrofurantoin in Acute Uncomplicated Lower Urinary Tract Infection in Young Women A Randomized, Open Label, Comparative Study

Anita K*, Razdan kaul A, Dhanesha G and Priyambada U

Department of Obstetrics and Gynaecology, Asian Institute of Medical Sciences, India
*Corresponding author: Anita K, Department of Obstetrics and Gynaecology, Asian Institute of Medical Sciences, Sector 21A, Faridabad, Haryana, India
Article Information: Submission: 02/12/2019; Accepted: 31/12/2019; Published: 03/01/2020
Copyright: © 2019 Anita K, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aim: The aim is to evaluate the comparative efficacy and safety of fosfomycin and nitrofurantoin in acute uncomplicated lower urinary tract infection in young women in our study cohort.
Material and methods: A randomized open label, intention to treat, comparative study was conducted over period of two years. Women were prescribed either nitrofurantoin or fosfomycin and their final outcomes in term of clinical and bacteriological cure were compared.
Results: Both the drugs were found to be equally effective in treating UTI with comparable safety and tolerability.