Case Report
Case Report: Anti-NMDA Receptor Autoimmune Encephalitis in a Young Female
Gopi Krishnan R*, Ravikumar V and Gunasekaran A
Department of Neurology, Thanjavur Medical College, Tamilnadu, India
*Corresponding author:Gopi Krishnan R, Department of Neurology, Thanjavur Medical College, Tamil Nadu, India. E-mail Id: gkr.619@gmail.com
Article Information:Submission: 18/05/2025; Accepted: 11/06/2025; Published: 16/06/2025
Copyright: ©2025 Gopi Krishnan R, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This case report describes a 23-year-old female who presented with progressive hypersomnolence, neuropsychiatric symptoms, and oro-mandibular dyskinesia. Diagnosis of anti-NMDA receptor autoimmune encephalitis was confirmed through cerebrospinal fluid (CSF) analysis, which revealed anti-NMDA
receptor antibodies. Prompt immunotherapy and supportive care led to clinical improvement. This case underscores the importance of early recognition and intervention in autoimmune encephalitis, particularly in young patients with atypical neuropsychiatric features.