Case Report
Acute Peritoneal Dialysis in Phenobarbitone Toxicity
Prashant Bharat M1*, Mukund A2, Sunita A3 and Deepak M3
1Department of Medicine, DNB Nephrology, Assistant Professor, Government medical college and hospital, Akola, Maharashtra, India
2Department of Medicine, MD Medicine, Government Medical College and Hospital, Akola, Maharashtra, India
3Department of Medicine, resident, Government Medical College and hospital, Akola, Maharashtra, India
2Department of Medicine, MD Medicine, Government Medical College and Hospital, Akola, Maharashtra, India
3Department of Medicine, resident, Government Medical College and hospital, Akola, Maharashtra, India
*Corresponding author: Prashant Bharat M, Department of Medicine, DNB Nephrology, Assistant Professor, Government Medical College and Hospital, Akola, Maharashtra India. E-mail Id: prashant_malviya37@yahoo.co.in
Article Information: Submission: 29/09/2023; Accepted: 02/11/2023; Published: 08/11/2023
Copyright: © 2023 Prashant Bharat M, et al. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Barbiturates are rare cause of poisoning and they are said to be cause of 15 per cent of all poisoning cases. It can be intentional or unintentional. Most patients improve by conservative management. But few patients develop progressive deterioration requiring ventilator support. Drug elimination in these
patients will save patients life and shorten recovery period. We report a case of 26 yrs. old female with severe phenobarbital poisoning complicated with hypotension, respiratory depression requiring ventilator support and very high inotropic support. She was initiated on alkaline diuresis but had poor response.
In view of hemodynamic instability she was initiated on peritoneal dialysis. Patient underwent 50 cycles of peritoneal dialysis over 4 days. Her general condition improved with inotropic support stopped on day 3 and ventilators were removed on day 4. Very few patients of barbiturate poisoning treated with
peritoneal dialysis are reported till date.
Keywords: Peritoneal Dialysis; Barbiturate Poisoning; Phenobarbitone