Treacher-Collins syndrome or Mandibulofacial dysostosis (MFD) is a rare congenital disorder with autosomal dominant inheritance, associated with aberrations of craniofacial development. The most common clinical features include malar bone and mandibular hypoplasia, antimongoloid slanting of palpebral fissures, and other ear abnormalities. Computed tomography is the imaging modality of choice for the morphological analysis of the craniofacial bones in individuals with complex facial deformities and to assist in the planning of surgical intervention. We present a case of unilateral mandibulofacial dysostosis with absent middle ear ossicles.

Keywords:Treacher-Collins; Middle Ear Ossicles; Computed Tomography; Zygomatic bone